Paying attention to the safety of children’s medication: from the "children’s prohibition" of Bupleurum injection

  CCTV News:A few days ago, official website City, National Medical Products Administration issued an announcement to revise the instructions of Bupleurum Injection, in which "Children are forbidden" was added to the taboo. For people born in the middle and late 20th century, this is undoubtedly a kind of "emotional robbery" from childhood, so that when it is mentioned that "another commonly used drug for children has become a banned drug", many people may not remember that this drug was recommended for use because of its "few side effects", but they can always recall the "myth" of "going to the hospital with a fever, and getting an injection at their parents’ words" the disease will be cured ". … After the injection, I was still crying and being carried out of the hospital by adults.

  Back to reality, Bupleurum injection will "quit" the ranks of antipyretic drugs for children. According to insiders, in pharmacy, banned drugs are the most stringent restrictions and must not be used. What does this mean? Some analysts said that this is a sign of progress, which is good from the perspectives of clinical safety, Chinese medicine supervision and economic benefits.

  What are the reasons for the change from "commonly used drugs" to "prohibited drugs"? 

  In the 1940s, Bupleurum injection, as the world’s first traditional Chinese medicine injection, began to be used in clinic. At that time, during the Anti-Japanese War, drugs were scarce, and Bupleurum was boiled into decoction, which was further made into injection by decocting and distilling to treat fever caused by colds and malaria. In that special period, it played a certain role. According to insiders, "Bupleurum Injection" is a beneficial attempt of traditional Chinese medicine injection, but it is not a successful product.

  As early as 2007, Bupleurum Injection was listed in the "List of Injections with Serious Adverse Reactions" by the State Food and Drug Administration. National Medical Products Administration requested to add warning words in the revision of the instruction manual of Bupleurum Injection. The contents should include: the adverse reactions of this product include anaphylactic shock, which should be used in medical institutions with rescue conditions. Users should be trained in anaphylactic shock rescue, and allergic reactions or other serious adverse reactions after taking the drug should be stopped immediately and treated in time. The report and monitoring of adverse drug reactions directly affect the use of drugs. An important job of hospital pharmacists is to observe, collect and sort out adverse reaction reports, and report them to the ADR monitoring center through the monitoring system at the first time. At the same time, through the analysis of the collected adverse reaction reports, preventive measures to prevent adverse reactions are put forward to ensure the safety of patients’ medication.

  With the gradual improvement of drug management, the concept of disease treatment is also developing. In the past, it was said that "a shot will cure you", but now when you walk into the hospital, the slogan "You can take it orally without intramuscular injection, but you can inject it without infusion" can be seen in the fever clinics of hospitals at all levels. Insiders pointed out that at present, China’s drug use for special groups such as children and pregnant women is more strictly regulated. This is a matter of principle and is in line with international practice. At present, Bupleurum injection is widely available, safe and effective for children to reduce fever. Under the principle that it can be taken orally without intramuscular injection, it is reasonable for Bupleurum injection to be changed from a commonly used drug for children to a banned drug.

  The proportion of injections in adverse drug reactions remains high. According to the National Annual Report on Adverse Drug Reaction Monitoring (2017), according to the statistics of drug administration routes, intravenous drug administration accounted for 61% of adverse drug reactions/events reports, up 1.3% over the previous year; The monitoring reports in recent two years show that injection accounts for more than 80% of the distribution of drug dosage forms involved in children’s adverse drug reactions/incidents reports. Re-evaluation of drugs after listing is undoubtedly the top priority.

  What does the re-evaluation of traditional Chinese medicine injection reflect?

  In the 1970s, there were more than a thousand kinds of traditional Chinese medicine injections, but there were quite a few or even the vast majority of basic research deficiencies and defects. This has also become one of the reasons for frequent adverse reactions of traditional Chinese medicine injection. In 1985, China implemented the Drug Administration Law, and the supervision of traditional Chinese medicine injections was gradually strengthened. Drugs with large side effects and low safety began to be phased out. By the 1990s, after rectification, the varieties of traditional Chinese medicine injections were 10 times lower than before — — There are more than 100 varieties. In view of the safety problems of more than 100 kinds of traditional Chinese medicine injections or stocks, in 2002 and 2006, National Medical Products Administration has been rectified twice.

  The "2017 Drug Evaluation Report" released in March 2018 pointed out that the key work to be carried out in 2018 includes studying and starting the re-evaluation of traditional Chinese medicine injections and formulating the technical guiding principles for re-evaluation. It is worth mentioning that Jiao Hong, the director of National Medical Products Administration, who took office in March 2018, had been in charge of the field of medical devices for a long time. As soon as he took office, he intensively conducted research in the field of traditional Chinese medicine, and listened to the constructive opinions of relevant experts on the re-evaluation of traditional Chinese medicine injections, the supervision of traditional Chinese medicine decoction pieces and traditional Chinese medicine formula granules, and the proper handling of landmark upgrading to the national standard. Insiders pointed out that these directly refer to the problems left over from the history of traditional Chinese medicine.

  In October 2017, the General Offices of the General Office of the Central Committee of the CPC and the State Council issued the Opinions on Deepening the Reform of Review and Approval System and Encouraging the Innovation of Pharmaceutical Medical Devices, proposing that the review and approval of pharmaceutical injections should be strictly enforced, and the listed pharmaceutical injections should be re-evaluated according to the progress of pharmaceutical science, so as to be basically completed in about 5 to 10 years. At that time, Bi Jingquan, the former director of the State Food and Drug Administration (now the Party Secretary of the State Administration of Markets), had to accelerate the evaluation of consistency of drug quality and efficacy, explore the methods of consistency evaluation of injection quality and efficacy, and start the re-evaluation of the safety and effectiveness of traditional Chinese medicine injections.

  As early as July 2009, the State Food and Drug Administration issued a series of documents, such as "Notice on Doing a Good Job in Safety Re-evaluation of Traditional Chinese Medicine Injections", and started the re-evaluation of the safety of traditional Chinese medicine injections, which has achieved initial results.

  Looking back on the road of "re-evaluation" of traditional Chinese medicine injections in recent 9 years, it can be described as twists and turns. According to insiders, the reason is nothing more than two points: high cost and lack of enthusiasm of pharmaceutical companies; It is difficult to implement and the working rules are not clear. In order to make the development of Chinese medicine industry more orderly and meet the people’s demand for drugs, we must persist in taking the people as the center, deepen the reform of the evaluation and approval system, and ensure that all reform tasks are put in place within the time limit.

  Children’s safe drug use is a cliche. How to come up with new ideas?

  Let’s go back to another protagonist of Bupleurum injection "Children are forbidden". There are 280 million children in our country, and the country is strong if the children are strong! Let children grow up healthily and happily, which is the greatest wish and expectation of every family, and also the foundation and support for the country to become prosperous and strong. We should always give priority to the healthy development of children and promote the priority supply of drugs for children.

  At present, the current situation of children’s medication in China is as follows: among more than 6,000 pharmaceutical enterprises, there are only more than 10 enterprises specializing in the production of children’s medication, accounting for about 0.17%; There are more than 3,600 kinds of prescription drugs for adults, and only more than 60 kinds of special drugs for children, less than 1.7%; There are more than 176,000 drug approvals in China, but there are only more than 3,500 children’s drugs, accounting for only 2% of the total drug approvals.

  The shortage of drugs for children is mainly affected by three factors: imperfect laws and regulations such as market access and price policy; Drug research and development is difficult, and children’s drug research and development is one of the most expensive, time-consuming and complicated fields in clinical trials, and it is difficult to recruit (children volunteers) for clinical trials; The market space is small.

  The report of the 19th National Congress of the Communist Party of China proposed to improve the drug supply guarantee system. In view of the shortage of children’s drugs and the lack of research and development motivation, the state has also introduced a series of policies and measures. In the 2017 edition of the medical insurance drug list, 91 kinds of children’s drugs were added, and there were 540 drugs or dosage forms clearly suitable for children in the drug list; The priority evaluation system for children’s medication has been continuously improved, and the protection of children’s medication has been strengthened; In the State Council’s opinion on drug procurement, it is suggested that generic drugs for women and children can be directly purchased online without bidding, but these are far from enough.

  To solve the problem of children’s drug shortage, some experts said that traditional Chinese medicine with relatively mild properties has become a new field of children’s drug research. Classic prescriptions, historical prescriptions and folk prescriptions have relatively exact effects on the treatment of children’s diseases and should be used scientifically and reasonably. In the government work reports of the two sessions this year, it is pointed out that it supports the inheritance and development of Chinese medicine. While inheriting ancient books, we should further promote the utilization and development of traditional Chinese medicine by means of modern science and technology. (Text/Zhang Ke)

Real kung fu! Three Shandong guys made their own martial arts films and became popular. Netizen: It’s worse than the movie.

This article is reproduced from WeChat WeChat official account Qilu Evening News (ID:qiluwanbao002)。

What is the hottest kung fu on the short video platform recently? That must be the "Goro Bagua Stick".

Recently, Shandong guys Wang Qun, Sun Xingang and Zhang Jikun, who have been practicing martial arts since childhood, made their own martial arts films and uploaded them to the online platform through video recording. Unexpectedly, they unexpectedly became popular. The hottest video work "Five Lang Bagua Stick" has won more than 2.6 million praises from the public.

Click to view larger image.

When recording a video, devote yourself to it. When broadcasting live, you are naughty and humorous.

"The Kung Fu Dream of the two uncles (Wu Kong)" is the Tik Tok uploaded by Wang Qun, Sun Xingang and Zhang Jikun, and their names are "Kung Fu" and "Humor".

What really made the three people popular was the 45 real kung fu videos uploaded by them, among which the most popular work was the "Goro Bagua Stick" with over 2.6 million praises. Judging from the video, their every move and every style is devoted. After the live broadcast, the three were naughty and humorous, and the interaction with fans was very casual.

Wang Qun told reporters that all three of them have been practicing martial arts since childhood, from Yantai, Weihai and Liaocheng, Shandong Province, and met in the Wushu Department of Chengdu Institute of Physical Education. At school, they were attracted by each other’s martial arts. After leaving the campus, Wang Qun runs a biotechnology company, Sun Xingang runs a teahouse, and Zhang Jikun has experience in martial arts instruction, and is knowledgeable in choreography and post-editing. Although they are engaged in different industries, they still come together with the same martial arts dream.

"You may not believe it when you say it. The idea of starting to shoot videos was talked about when we were sitting together for tea." Wang Qun said that when they talked about practicing martial arts that day, they didn’t have such advanced mobile phones and shooting equipment, and their previous training was not recorded. The three men proposed to realize their dream of a martial arts film by video recording, and at the same time, they could make a record of their martial arts, and the three men hit it off.

A month ago, they shot the first video and uploaded it to the short video platform, which gained more than 4,000 likes, which brought them confidence. "I didn’t expect so many people to like it. We three big boys got together to discuss whether to continue filming, and finally decided to continue filming." Wang Qun said.

Every time the video is shot, the three people play the action and plot on the spot. From left to right are Sun Xingang and Wang Qun. (Photo courtesy of the interviewee)

Every scene shooting is improvisation and plot.

Talking about the "Five Lang Eight Diagrams Stick" with more than 2.6 million praises, Wang Qun introduced that this video belongs to a relatively long shooting and production cycle. "It takes three or four days to shoot the video, plus two days of post-production, and it takes almost five or six days to do it well." Wang Qun said that the shooting cycle of some small clips is relatively short. For more than a month, they have basically maintained the frequency of updating every two days, and it takes about three or four days to shoot and post-produce.

In the uploaded videos, the real kung fu of the three people won everyone’s praise and recognition. In fact, these videos were not produced by a professional team. "Only the three of us, plus a photographer." Wang Qun said that since the explosion of fire on the Internet, many people have also asked them if there is a professional team operating.

In fact, every time the video is filmed, the three of them are improvising actions and paragraphs on the spot, and then adding the plot. Because many times three people need to appear in a martial arts film at the same time, they hired a professional photographer. If it is a relatively simple plot, Zhang Jikun, who has worked as a martial arts instructor, will shoot it himself and do the post-production.

Click to view larger image.

Nanchang area e π 008 price reduction information! The latest offer 188,600, only this time

Title: [Autohome Nanchang Promotion] A strong attack, Nanchang car purchase enjoys the highest 28,000 discount!

In this exciting moment, consumers in Nanchang area are blessed! Autohome Nanchang preferential promotion channel has joined hands with dealers to bring a car-buying feast that cannot be missed for the majority of consumers. As the focus of the preferential car series, eπ 008 is carrying out a grand price reduction activity in Nanchang area. It is understood that buyers of eπ 008 can enjoy a cash discount of up to 28,000 yuan, making the already highly competitive price more attractive. The minimum starting price has been adjusted to 188,600, providing Nanchang citizens with real car-buying benefits.

If you are yearning for the eπ 008, now is a good time to make a move. Don’t miss this once-in-a-lifetime opportunity, click "Check Car Price" in the quotation form, let’s reveal more detailed discount details together, and strive for the most cost-effective car buying experience. Hurry up and seize the car buying opportunity brought by this Nanchang eπ 008 price reduction discount!

南昌地区eπ008降价信息!最新报价18.86万,仅此一次

车系eπ008以其流线型的车身设计,勾勒出优雅而动感的侧面轮廓。车身尺寸为5002mm*1972mm*1732mm,轴距长达3025mm,展现出宽敞的内部空间。前后轮距均为1650mm,确保了优秀的行驶稳定性。轮胎规格为265/45 R21,搭配精致的轮圈设计,不仅提升了车辆的视觉冲击力,也保证了行车的抓地力和舒适性。整体来说,eπ008的侧面线条饱满有力,彰显出豪华与科技的完美融合。

南昌地区eπ008降价信息!最新报价18.86万,仅此一次

内饰方面,eπ008展现出简约而精致的设计风格,中控台上搭载了一块15.6英寸的超大触控屏,提供清晰、直观的操作体验。方向盘采用质感优良的皮质材料,不仅触感舒适,还支持手动上下+前后调节,确保驾驶员的操控便捷。车内配置了语音识别控制系统,可方便地控制多媒体、导航、电话和空调等功能。座椅方面,采用仿皮材质,注重乘坐舒适性,主副驾驶座均配备前后调节、靠背调节、高低调节以及腰部支撑,同时还具备加热和通风功能,确保四季皆宜的乘坐体验。驾驶位和副驾驶位还配备了电动座椅记忆功能,而第二排座椅则支持前后调节、靠背调节和腿托调节,空间利用合理,满足乘客个性化需求。此外,车内USB和Type-C接口数量丰富,前排2个、后排3个,满足乘客的充电和数据传输需求,手机无线充电功能也在前排位置贴心设置。

南昌地区eπ008降价信息!最新报价18.86万,仅此一次

车系eπ008搭载了一台1.5T涡轮增压发动机,能够输出147马力的强大动力,最大扭矩达到了210N·m。这款发动机匹配了电动车单速变速箱,提供高效且节能的驾驶体验。

总的来说,车主对eπ008的外观表达了高度的认可,认为其大气且符合个人喜好,特别推荐白色车身,既时尚又省去了额外的个性化费用。这样的评价无疑为有意购买的消费者提供了实用的参考,让eπ008在外观设计方面赢得了更多潜在车主的心。

Lexus RX in Tianjin is on sale, and the discount is 20,000! The discount waits for no one

[Autohome Tianjin Promotion Channel] Bringing you good news, the high-profile luxury SUV is going through a very strong promotion in the Tianjin market. Currently, car buyers have the opportunity to enjoy up to 20,000 yuan in cash, making this luxury model even more attractive with a starting price of up to 422,000. For consumers who are interested in buying a Lexus RX, this is a great opportunity not to be missed. To learn more about specific offers, click "Chatti Car Price" in the quote form and let our professional team help you get the best price.

天津地区雷克萨斯RX特价出售,优惠2万!优惠不等人

With its unique design concept and exquisite craftsmanship, the Lexus RX presents an elegant and dynamic appearance. The front face is designed with exquisite atmosphere, and the air intake grille adopts a family-style spindle design, giving the vehicle a high degree of recognition. The overall lines are smooth and the body profile is full, exuding the dual charm of luxury and power, showing the Lexus brand’s persistent pursuit of detail and aesthetics.

天津地区雷克萨斯RX特价出售,优惠2万!优惠不等人

With its elegant body proportions and exquisite side design, the Lexus RX shows a unique luxury temperament. The body size is 4890mm long, 1920mm wide, 1695mm high, and the wheelbase reaches 2850mm. This size setting provides passengers with a spacious interior space. In terms of tire specifications, 235/60 R19 specifications are used on the front and rear, which not only ensures driving stability, but also complements the overall design of the vehicle. The smooth lines on the side of the car, coupled with the exquisite wheel rim design, show Lexus’s persistent pursuit of detail and consideration for driver comfort.

天津地区雷克萨斯RX特价出售,优惠2万!优惠不等人

The interior design of the Lexus RX shows a combination of elegance and luxury, and exquisite craftsmanship and materials highlight the brand’s attention to detail. In the cockpit, the steering wheel is made of high-grade leather, which not only feels delicate to the touch, but also supports electric up and down + front and rear adjustment to ensure that the driver always has the best grip experience. The central control area is equipped with a 9.8-inch high definition touch screen, with a simple interface and supports automatic speech recognition, which is convenient for users to operate various functions such as multimedia, navigation and telephone. As for the seats, the main and passenger seats are made of imitation leather, providing multi-directional adjustments such as front and rear, backrest, height and waist support to ensure the comfort and support of the ride. The rear seats support backrest adjustment, the space layout is flexible, and there is a proportional reclining function to meet the needs of different scenarios. Overall, the interior design of the Lexus RX is designed to create a warm and technological driving environment.

天津地区雷克萨斯RX特价出售,优惠2万!优惠不等人

The Lexus RX is equipped with a 2.5-liter L4 engine with a maximum power of 139 kilowatts, providing abundant power to the vehicle. Its torque output reaches 241 Nm, and with the E-CVT continuously variable transmission, it ensures a smooth driving experience and high-efficiency performance.

Overall, Autohome owners’ comments on the Lexus RX fully reflect its outstanding design and craftsmanship. The "extravagant" and "attractive" elements he mentioned, as well as the technological upgrade of the "spindle" grille, all add a lot to the RX. For consumers who pursue quality and detail, the Lexus RX undoubtedly meets their expectations. Whether it is the appearance or the interior, it highlights the Lexus brand’s insistence on luxury and elegance, making it stand out among many luxury SUVs.

Which is the best driving platform? Which is better, e-driving and Didi driving?

At present, the top ten driving companies are e-driving, Didi driving, hitchhiking, (| |) driving, Ai driving, micro driving, etc. Among them, e-driving and Didi driving are relatively well-known and are also among the best in the driving industry. Many friends who want to join the ranks of driving are hesitant and do not know which driving platform is better. Today we will discuss the situation of e-driving and Didi driving in detail, and give some guidance and suggestions.

Which platform is better?

E-driving status quo: At present, more than 100,000 drivers and 500,000 users have registered, and the business covers 200 cities. It is the first driver platform that has been deployed and entered the market. It has certain advantages in hardware, service system, word-of-mouth and brand. User experience is the hottest, coolest and most practical mobile client side.

Didi driving status quo: a one-stop travel platform including taxis, special cars, express trains, hitchhikers, chauffeurs, and buses. The diversity of services allows more users to choose Didi driving, and it also has many advantages such as driver resources and platform big data, which has won a certain reputation.

Love the status quo of chauffeur driving: China’s chauffeur driving industry is a fast, safe and reliable professional drunk driving service. Starting at 38 yuan is cheaper than a taxi, but it is not as popular as the first two.

Micro Driver Status: It is an application that solves various needs such as drunk driving, business driving, long-distance driving, renting a car, and driving test sparring.

In general, each major driving platform has its own advantages, e-driving and Didi driving have more advantages. Let’s analyze it in detail below.

Which is better, e-driving and Didi-driving?

1. As for how much money Didi and e-driving can earn a month, according to the driver’s report, most of the orders for part-time drivers at night are after ten o’clock in the evening, and one order is more than 100. You can earn about 150 yuan for two or three orders a night, and the driver can earn 2000-3000 yuan a month. No problem.

2. Didi driving and e-driving platforms are a problem. The driver also mentioned that if you drive 10% -20% for a single drive, Didi will have driver points. If the cancellation is greater than 20%, the corresponding points will be deducted (12 points a year), and the e-driving platform will even give the offending driver a ban.

3. Platform scheduling rules. Both platforms adopt the rules of customer self-service or system dispatch. The client side can display the information of the nearest driver. Select one of them or place an order with one click to call the driver for door-to-door service. But the system dispatch requires the customer to place an order on behalf of the driver and make an appointment according to the time of the customer’s appointment.

4. Platform charging standards. Since the charges vary slightly from place to place, in general, the charges for e-driving will be higher. If you want to drive part-time, you can choose e-driving. For details, please click (Didi driving charging standards) or (e driving charging standards) to view.

5. Liability for driving accidents. Didi driving platform liability protection of up to 3 million yuan per order brings greater protection to drivers and passengers when contemporary drivers have accidents. E driving platform liability insurance maximum compensation 2 million.

The female owner said that the new M7 intelligent driving mode crashed, and there is a hidden danger of sudden braking after picking up the car for seven days

Ms. He was attracted by the online promotion of the M7 Smart Driving Edition of Wenjie, especially its claim that the "smart driving pilot" technology is far ahead and the concept of "safety is the greatest luxury". So she decided to replace it with a Cadillac at home, bought the M7 Smart Driving Edition priced at 300,000 yuan, and picked up the car on February 28.

Female car owner claims to have crashed in Jiexin M7 intelligent driving mode

However, only on the seventh day of pickup, Ms. He encountered problems when using the Smart Driving Pilot function. At that time, the vehicle was driving at a speed of 60 yards on an elevated or high-speed road. Although there was no car ahead and the environment was safe, the vehicle suddenly braked suddenly, which could easily lead to a rear-end collision. The video provided by Ms. He clearly recorded the sudden situation: the vehicle suddenly braked for no reason after turning on the Smart Driving Pilot, and there was no obstacle ahead.

The female owner said that the new M7 intelligent driving mode crashed, and there is a hidden danger of sudden braking after picking up the car for seven days

After discovering the problem, Ms. He and the staff of the 4S shop went on the road to test the car, and found a new problem – the body was shaking all over. In addition, the navigation solid line lane change function was abnormal, and the smart driving function would exit without warning.

The female owner said that the new M7 intelligent driving mode crashed, and there is a hidden danger of sudden braking after picking up the car for seven days

When the reporter accompanied Ms. He’s husband to experience the elevated driving, the vehicle repeatedly exited and re-entered the smart driving mode near the section of Wenyi West Road in Hangzhou Desheng Elevated Road, during which similar failures occurred many times. In this regard, Ms. He said that in the process of using the smart driving pilot function five times, the failure rate was as high as 100%, which raised questions about its safety.

Geely Xingyue with a wheelbase of 2.8 meters is L, and its size exceeds Tiguan L, but it is positioned as a compact SUV.

A few days ago, the brand-new SUV-Xingyue L completed its debut. I believe many people, like me, will regard this new car as a medium-sized SUV when they see its body size. After all, its length is nearly 4.8 meters, and its wheelbase is over 2.8 meters. The "block" is already bigger than Tiguan L. But the official defines it as a compact SUV. Why?

Low-key positioning, just for misplaced competition?

Let’s take a concrete look at the body size of Xingyue L. Its length, width and height are 4770/1895/1689mm and the wheelbase is 2845 mm. We choose two popular medium-sized joint venture SUVs to compare with them. As can be seen from the following table, the Star Yue L, which locates compact SUVs, is bigger than Tiguan L and Highlander.

In this regard, the official did not give a specific explanation. Personally, in today’s endless market segments, the so-called positioning of the model itself is very vague. Because of this, many car companies choose to compete in dislocation and compete with their opponents, such as Xingyue L.

As we all know, the price range of 100,000 to 150,000 is the main position of the independent compact SUV, and the price range of 150,000 to 200,000 belongs to the "site" of the joint venture compact SUV. If the autonomous SUV wants to cross the 150,000 hurdle, it can only choose dislocation competition. For example, UNI-K, which was listed before, used the identity of medium-sized SUV to compete with joint venture competitors.

Although the specific price of Xingyue L has not been announced yet, it can be boldly speculated that its starting price will not be low, at least above 150,000, maybe 160,000 or 170,000. If this is the case, then the price range of Xingyue L is almost "flush" with that of other models. From the price to the vehicle positioning, this is a real positive competition, which can reflect the confidence of the car. Of course, it is undeniable that from the product strength of the model itself, Xingyue L still has leapfrog advantages.

The highlight of Xingyue L: the engine pulls the eye.

So where is the leap of the star over L? In addition to body size including space, power is a bright spot. Its whole system is equipped with Drive-E series engines, and 2.0T provides high and low power output, which is divided into 218 horsepower and 238 horsepower. It is worth mentioning that the low power version matches the 7-speed wet dual-clutch gearbox, while the high power version matches the 8AT gearbox.

Combined with the estimated price, it is very likely that you can buy a version of 2.0T with 8AT for less than 180,000 yuan. You know, the joint venture models corresponding to this price are almost entry-level power, 2.0L self-priming or 1.4T small displacement engines. And Xingyue L is very competitive in terms of displacement and label (). In addition, Xingyue L will also be equipped with the sixth-generation Borgwarner four-wheel drive system, which is hard enough from the perspective of three major pieces.

In addition to the three major pieces, another highlight of the Star Yue L is the sense of design and materials, especially the interior parts. Different from previous models, the Star Yue L highlights the sense of technology on the one hand and adds a sense of luxury at the same time. This sense of luxury is more like a breakthrough. For example, in the interior, a lot of rose gold decoration has been added, which has been seen on the model before and is very textured; At the same time, with custom leather and brown plaques, the luxury atmosphere is in place.

It is worth mentioning that the steering wheel of Xingyue L adopts the design of two-color leather, which makes people shine again visually. When it comes to the sense of science and technology, Xingyue L has also made a breakthrough. In addition to the full LCD instrument screen, it also adopts the form of central control and co-driver’s joint screen, which is a bit of a new force. I believe that in terms of function, it can also give people a different experience.

Achuan pingche

In fact, it’s not the first time to take the misplaced positioning route. The previous Xingrui, with a wheelbase of 2.8 meters, is still positioned in a compact car, and the reason is the same. For Xingyue L, the final pricing is very important, because it has to compete with the joint venture compact SUV, but also with competitors at the same level such as UNI-K and Mocha. Every step is the key point to decide the outcome.

Extreme krypton started a sideline: holding the vast -M architecture and building cars for autonomous driving companies.

Does the company have to build cars?

With the mature development of the industrial chain, autonomous driving companies can generally come up with autonomous driving sensor kits specially designed for Robotaxi scenes and in line with in-vehicle applications and standards.

In their view, building a car in the next stage is not only time-consuming and costly, but also has many technical barriers. It also needs to build its own factory and build an upstream and downstream industrial chain.

At the same time, there is another voice in the industry that adding sensor kits, technical units and software to the original vehicles is no longer in line with the next development goal of autonomous driving.

In other words, building a car will become the most critical step in promoting the commercialization of autonomous driving.

In July 2022, Baidu Apollo released the first unmanned vehicle RT6, which broke the dilemma that Robotaxi was mostly a modified car, and the cost of RT 6 was reduced to250 thousandYuan.

On November 17th, 2022, the M-Vision concept car jointly developed by Waymo and Krypton made its debut in Los Angeles. The new car was based on Krypton Vast-M.(SEA-M)The architecture will be mass-produced in 2024 and put into commercial operation in the United States.

In their view, autonomous driving wants to achieve large-scale mass production of technology, vehicle platforms need to be innovated, and software and hardware systems need to be more deeply integrated.

This means that the carrier of autonomous driving needs to draw a blueprint from a blank sheet of paper.

"It is an inevitable trend for unmanned vehicles to develop from refitting and installing finished vehicles to customizing and developing based on vehicle platforms. An industry person said.

01、I started a sideline and built a car for Waymo.

In December 2021, Waymo officially announced a cooperation with Krypton. The latter will provide exclusive vehicles for Waymo’s self-driving fleet and put it into commercial operation in the United States.

A year later, the M-Vision concept car, the result of cooperation between the two parties, made its debut in Los Angeles.

According to the heart of the car, Waymo is responsible for the automatic driving system and cockpit entertainment system, while the European Innovation Center is responsible for providing the core components of Robotaxi.Vast -M architecture.

In fact, Krypton was able to cooperate with Waymo without two acquisitions.

In July 2021, it was extremely embarrassing.1,057.8 millionkoruna(about 799 million yuan) Acquired CEVT in Gothenburg, Sweden(China-Europe Technology Research and Development Center)100% equityLater, it was renamed the European Innovation Center.

After the acquisition, CEVT can provide shared architecture, chassis, powertrain, transmission system, car body and vehicle design technology for future strategic products and R&D platforms.

CEVT is a gathering place of technical souls.

Since its completion and operation in 2013, CEVT has been Geely.1.3 millionThe production and sales of this car provide a complete and systematic technical system, and have trained thousands of global technical talents. The well-known CMA architecture and so on are all from this R&D center.

The second acquisition comes from the 30% equity acquisition of vast energy. This acquisition enables Krypton to redevelop the vast architecture of SEA.

In short, combined with the technical advantages of Krypton European Innovation Center, Krypton can develop the vast architecture again-this is also the origin of the vast -M architecture.

Vast -M is developed based on the vast architecture of Geely SEA, which took Geely five years to invest.20 billionThe pure electric architecture developed is also the killer of Geely in the field of new energy.

The characteristics of Geely’s vast architecture can be simply summarized into three key words:

According to Krypton, Haohan -M is the world’s first intelligent mobile travel platform specially developed for autonomous driving scenes, and it is the latest type of vast architecture facing the era of autonomous driving.

Among them, the m of vastness -M stands for Modular Mobility Architecture(Modular Travel Architecture).

On the basis of prototype architecture, Vast -M passedhardware layer+System layer+Ecological layerTo create a sustainable and extended self-driving vehicle.

To achieve this, we not only rely on the vast prototype architecture to cover the high application range of 1800-3300mm wheelbase of A-E class cars, but also need a native electric platform and flexible expansion ability to support L4 class automatic driving.

In this regard, it is almost impossible to achieve the traditional fuel vehicle platform, and related problems have been exposed in oil-to-electric vehicles before.

Constrained by a large number of complicated mechanical transmission structures, the expansion and layout adjustment capabilities of the traditional fuel vehicle platform are very limited, and the motors can only be installed in the space left after the fuel tanks are cancelled, so it is difficult to adjust the vehicle structure.

It can be said that holding the advanced vast -M architecture, he started a sideline business-helping autonomous driving companies build cars, which directly contributed to Waymo’s choice of cooperation.

Vast -M architecture, fully embedded with automatic driving interface, can be connected to the automatic driving system of L4 level and above, and can be compatible with different automatic driving schemes, from local control to full control of vehicles.

In addition, the vast -M architecture meets all technical requirements of autonomous vehicles and is compatible with all autonomous driving schemes.

"From Waymo’s point of view, it is extremely difficult for Krypton or Geely Group to find a second partner because of its ability to control costs under the same quality and its European R&D and innovation capabilities. 」

When talking about why Waymo chose to cooperate with Extreme Krypton to develop customized cars, Yang Dacheng, vice president of Extreme Krypton, said.

"The vast -M architecture is open to ecological partners around the world, not just Waymo, but also other global autonomous driving companies."

Through the cooperation case with Waymo, Yang Dacheng also threw an olive branch of "OEM" to other autonomous driving companies.

In the past, the threshold of "OEM" was not high, just providing enough assembly experience to achieve the production target.

Nowadays, due to the special products such as self-driving cars, the traditional cooperation mode is directly broken, and at the same time, the "OEM" needs to export certain research and development capabilities.

02、What’s different about Robotaxi, which Waymo cooperates with Krypton?

As a leader in the field of autonomous driving, Waymo has also tried to build his own car.

In May 2014, the autonomous driving team released a code-named ""fireflyThe unmanned car is planned to invest 100 vehicles in a small-scale trial operation in California in the early stage.

Due to the imperfection of the supply chain, the cost of Firefly is high, and the original 100 cars were finally cut down.50 vehiclesCar, coupled with the slow progress of the project, Google finally gave up its own car-making route.

In 2017, Google announced the retirement of Firefly.

In 2018, Waymo made an ambitious announcement to purchase from Land Rover and Fiat respectively. 20,000 vehiclesI-PACE and62,000 vehiclesDajielong is used to build a self-driving fleet.

In order to expand the operation scale of the fleet, in 2019, Waymo announced the establishment of the world’s first factory to produce L4 self-driving cars in Michigan, USA, which is mainly responsible for modifying the purchased existing production cars.

Up to now, there is no sign that Waymo has achieved his goal.

According to public data, Waymo’s current fleet size is only over 1,000 vehicles, and the current practice is still to install automatic driving kits on production vehicles.

This seems to be efficient, but it will bring many problems.

The first is the vehicle.Basic quality. The existing control system of mass production vehicles is built on the basis of human drivers, and the basic functions, including throttle, braking and steering, are all completed by traditional mechanical transmission, but this is completely different operation logic for the automatic driving system that relies on electronic signals to control vehicles.

Followed by the vehicle.Functional scene. Self-driving cars are essentially liberating drivers. Starting from the needs of passengers, we define what kind of functional scenes a self-driving car should achieve. However, most existing production cars are just a family car with comprehensive functions, and the layout of the cockpit cannot be changed, which cannot further expand the practicability of the vehicle.

Finally, the vehicle’scost. The needs of C-end users and B-end users are different. To build a self-driving car and a family car, the investment of BOM cost is completely different.

When refitting on the existing vehicle platform, it is necessary to bear all the BOM costs of the original private car, and it is also necessary to superimpose the cost of the autopilot kit, which is a great challenge to reduce the cost, which also leads to the large-scale investment of the refitted car and the cost of bicycles.

From the perspective of scale, Waymo urgently needs a mass-produced Robotaxi model.

In the negotiation with Krypton, Waymo once put forward requirements for vehicles-comfort comparable to S-class, chassis control comparable to e-tron, vehicle energy consumption comparable, and required the service life of operating trucks.

On the one hand, due to Waymo’s strong dominance, car companies can only play the role of engineering development and vehicle manufacturing.

On the other hand, based on Waymo’s personalized requirements for vehicles, car companies are reluctant to develop an exclusive self-driving car platform from scratch. After all, the current commercial feasibility is far lower than the research and development cost.

This is why Waymo’s previous cooperation model with car companies is relatively simple.

Waymo only purchases complete vehicles from Fiat Chrysler, Jaguar Land Rover and-,and deploys the sensor kits needed for autonomous driving on these vehicles through modification, and then carries out the real road test of autonomous driving or the self-driving taxi test.

Looking at the world, there are very few companies that can enable autonomous driving companies like Waymo to achieve mass production based on the vast -M architecture.

To put it another way, whether an autonomous driving company wants to build a car depends largely on whether it can find a useful carrier.

Based on this kind of thinking, a route that can not only be developed from zero to positive, but also hand over the burden of building cars to partners has become a new choice for autonomous driving companies such as Waymo.

The first is inProduct experienceOn the level, different from the traditional car model focusing on the driver’s thinking, the mobile travel vehicle built by the vast -M architecture is oriented to the automatic driving application scene, and the biggest highlight is reflected in the "user" experience:

The wheelbase of the vast -M architecture itself covers 2700mm-3300mm, and such a wide range of wheelbase makes the model extremely scalable-the front and rear suspension of the vehicle can be adjusted, and the distance between the seat and the rear axle can be stretched, finally providing a flexible layout of the cockpit space.

The second iscost. For self-driving cars, cost has always been the most sensitive issue.

A modified model with an automatic driving system, the price is500-1 millionRenminbi. In this cooperation with Krypton, Waymo’s demand is "to get the best things with the least money".

Yang Dacheng said, "Based on the efficient universality and scale of the vast architecture itself, the vast -M architecture can meet the needs of users with different budgets. 」

The third isquality. M-Vision meets the global five-star safety standards and conforms to the American Highway Safety Insurance Association.(IIHS)Maximum safety requirements. M-Vision can guarantee 500,000 kilometers in five years and meet the requirement of 16 hours of uninterrupted operation every day.

As early as the launch of the vast architecture, Geely said that the vast architecture will launch products with full open road autopilot function in 2025.

The debut of M-Vision also marks the further verification of the intelligent planning of the vast architecture.

03、Extreme krypton press the "fast forward key"

Waymo provides autonomous driving technology, and Krypton provides highly customized exclusive vehicles-this cooperation mode provides a new problem-solving idea for the landing of autonomous driving.

In addition to Waymo, other autonomous driving companies can also realize the landing of autonomous driving products based on the vast -M architecture.

As the most important smart electric vehicle brand under Geely Holding, through the commercial cooperation with Waymo, the vast -M architecture can also be fed back to the passenger car market in the future, thus enhancing the competitiveness of the brand.

Not long ago, Yang Xueliang, vice president of Geely, revealed on the social platform:

"M-Vision is a customized Robotaxi for Waymo in the United States, and M-Vision also has plans to promote To C products. 」

It is understood that the vast -M architecture will retain two versions of steering wheel, pedal/steering wheel and pedal at the same time.

According to informed sources, there are currently two products under development in the vast -M architecture:

With the continuous growth of the launch and delivery of the second new car 009, the product matrix of Krypton is accelerating.

According to the previous plan, Krypton will cover cars, SUVs and sub-categories around three product lines: Z, C and M in the next two years:

At the same time, Krypton will enter the global market, and Krypton 001 will enter the European market in 2023.

At the beginning of its development, Krypton fully considered the European standard and American standard, and certainly did not rule out a larger scale in the future. Extreme CEO An Conghui said.

Behind the market opportunity game, production capacity is the key to break through.

"Krypton currently has a production capacity of 300,000 vehicles, so it is no problem to ensure production and delivery, because we have other factories. In recent years, the new factories have also comprehensively considered the production needs of electric vehicles, and can realize the manufacturing of vast architecture products in the fastest time. At the press conference of Krypton 009 in November this year, An Conghui said.

Up to now, Extreme Krypton 001 has become the sales champion of China brand 300,000 luxury pure electric vehicles for three consecutive months-a total of 60,000 vehicles have been delivered, and the average order amount has exceeded.336 thousand.

Through the performance of krypton sales, An Conghui’s "internal letter" to internal employees shows that:

"The success of a single product cannot bring about the sustainable development of a brand. The diverse needs of users require us to complete the product layout from single product explosion to multi-product development as soon as possible. 」

Different from the cooperation mode of the new forces in the head and the internal incubation mode of traditional car companies, it relies on Geely+Volvo’s car-making experience and technical resources, but from decision-making to the accumulation of marketing experience, it has gone through a complete process from 0 to 1.

In other words, Krypton is exploring a route that combines the technical background of traditional car companies with the flexibility and efficiency of new cars.

As you can see, based on "Geely+Volvo technical resources are the underlying logic.",as well as the self-evolution of users’ travel needs, it is accelerating to prove the feasibility of building a third track.

Reading | Young People’s "Partner" Socialization

  * This article is the 11th issue of Pindu in 2023.

  I ran into an acquaintance, but I didn’t see him for more than a month and thought he had lost a lot of weight, so I asked him for advice on the secret of losing weight. He told me: "I found some partners to lose weight, ran together and ate fat-reducing meals. Everyone encouraged and supervised each other every day. I didn’t expect the effect to be quite obvious."

  Weight loss partner? Seeing my doubts, my acquaintances told me with a smile that compared with my friends, the utility of "partner" is more clear, and it can be accurately subdivided, such as "meal partner", "game partner" and "gym partner". That is, from the joint participation of something, it ends at the end of cooperation; Highly in tune with a certain field, but emotionally independent. Because we only concentrate on the matter itself, we are both relaxed. The acquaintance said happily: "This time, I lost weight successfully, and’ Zuozi’ contributed a lot. The purpose of getting together is to lose weight. If you lose weight successfully, the mission of’ taking the child’ will be completed, and it will be automatically dissolved. There is no trouble with the relationship. "

  I am a person who seems to have a "flattering personality". Every time I go out with my friends, I always habitually compromise. For example, if I want to stay in a hotel and my friend wants to experience a B&B, then go to the B&B, even though it makes me feel unsafe, I may not sleep well all night. I wanted to taste local specialties, but my friend couldn’t get used to it and asked for a change of fast food, so I stopped insisting and just ate at will. I plan ahead and want to visit more scenic spots, but my friend is tired and prefers to sleep in his room, so stay in his room and play with his mobile phone in another place.

  With the "partner", it is completely different. You are used to staying in a hotel, and I am used to staying in a hotel; You like to eat special food, and I like to try it. You are energetic and want to look around, and I also want to visit all the scenic spots … We are in tune with each other in terms of tourism. If it’s not in tune, then find another one who is in tune, and no one has to accommodate anyone. The original purpose of everyone is to find people with the same hobbies and have a good time. If you are happy, I will be happy.

Reading | Young People's "Partner" Socialization

  I have read Xu Zhimo’s poem: You and I meet in the dark sea/You have yours/I have mine/direction/You remember it/You’d better forget it/The light that shines on each other at this meeting … This poem is very suitable for describing the relationship between partners. After meeting each other, the vast majority of the results are forgotten, but some will remember, and thus further develop.

  Xiaoyuan is an example. When she announced her engagement in a circle of friends, many of her friends were surprised. Everyone knows that Xiaoyuan has always been in fear of marriage, and has declined many people’s kindness to introduce her boyfriend. Why did you suddenly change your mind? Xiaoyuan told everyone shyly that some time ago, she found a "book partner" to read together and exchange reading feelings. This "book partner", like Xiaoyuan, especially likes reading, and they have similar views and have the same view on many things. Because there is no burden of "making friends", Xiaoyuan gets along with each other easily and happily, and unexpectedly discovers the "interesting soul" of each other. It happened that the other party also felt this way, so they naturally developed from "partners" to male and female friends until they "made a positive result."

  In fact, "partner" socialization is a kind of "shallow socialization" above strangers and below friends. This kind of relationship can not only inspire each other, but also cause no extra burden to each other because of the sense of boundary, which is very suitable for busy young people with increasing pressure. If you want to get rid of a person’s loneliness quickly, it is still feasible to find a precise companion.

  Author: Qiao Kaikai

[Editor in charge:

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Running required course, 7 days to form a correct running posture, 7 days to go to the education fever list >

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