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Metformin, seven more pharmaceutical companies entered the market.

Recently, National Medical Products Administration official website showed that the application for listing of metformin tablets (Ⅰ), (Ⅴ) and (Ⅴ) submitted by Hunan Huize Biomedical Technology/Hunan Jiudian Pharmaceutical Co., Ltd. was accepted by CDE. On April 11th, Zhejiang Huahai Pharmaceutical Co., Ltd. also submitted the application for listing of metformin tablets (VI) and (V) and was accepted.　

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China is the largest country in the world, and the number of patients ranks first in the world. The incidence of diabetes is increasing and showing a trend of younger age.

According to the data of the International Diabetes Federation (IDF), the number of adult diabetic patients in the world reached 537 million in 2021. As the country with the largest number of diabetic patients in the world, the number of diabetic patients in China increased from 90 million to 141 million in the past 10 years (2011 -2021), with an increase of 56%, equivalent to 13% of adults suffering from diabetes, and there are about 72.83 million adults.

As the pathogenesis of type 2 diabetes mellitus (T2DM) is complex, with the progress of the disease, single oral hypoglycemic drugs often cannot maintain ideal blood sugar control for a long time, and there will be many complications. More than 60% of patients need to be combined with other hypoglycemic drugs. Compound hypoglycemic preparation has the advantages of strong efficacy, high safety, convenient use, high compliance and high cost performance, and is widely used at present.

Metformin is suitable for adult patients with type 2 diabetes who are treated with eglinide and metformin hydrochloride. It is a simple compound single-tablet drug. Engelgin belongs to sodium-glucose cotransporter 2(SGLT-2) inhibitor, which can reduce the glucose reabsorption in kidney. Metformin hydrochloride can improve insulin sensitivity by increasing the intake and utilization of peripheral sugar.

The mechanism of the two hypoglycemic components is complementary, which can provide more powerful and lasting blood sugar control, and can reduce the number of tablets taken by patients, thus increasing the compliance of patients, and the improvement of compliance is also helpful to further improve blood sugar control.

The original research of metformin englejing was conducted by Boehringer Ingelheim and Lilly. In 2015, it was approved for listing by the US Food and Drug Administration, and in 2019, it was approved by National Medical Products Administration to enter the domestic market under the trade name of Ou Shuangjing.

In June, 2021, Hangzhou Zhongmei Huadong Pharmaceutical Company’s Metformin Engglinide Tablets (I) was approved to be listed in National Medical Products Administration, becoming the first imitation in China, and was exclusively included in the National Medical Insurance Catalogue Class B through medical insurance negotiation in December of the same year. The medical insurance price was 1.21 yuan/tablet (each tablet contained 500mg of Metformin Hydrochloride and 5mg of Engglinide). At present, Hangzhou Sino-American Huadong Pharmaceutical Co., Ltd. is still the only enterprise in China that has been approved to produce metformin.

According to the IQVIA database, the global sales of metformin Engel in 2020 was 505 million US dollars, an increase of over 30% compared with 2019.

In recent years, the sales scale of oral compound hypoglycemic agents in China is also growing rapidly. According to the data of Minenet, the market of oral compound hypoglycemic agents has increased from 800 million yuan in 2019 to over 2.2 billion yuan in 2021, with the growth rate as high as 58% and 68% in 2020-2021. The market potential of oral compound hypoglycemic agents is exploding.

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According to Frost&Sullivan data, the global diabetes drug market will reach 69.7 billion US dollars in 2020, and the Chinese diabetes drug market will reach 63.2 billion yuan. It is expected to reach 100 billion-level market in 2024, and will grow at a high speed with a CAGR of 10.4% from 2020 to 2030. The diabetes field has become a field that major pharmaceutical companies will strive for.

Hypoglycemic drugs are constantly innovating, and they don’t stop rolling up. Take Engelje as an example. At present, there are 5 domestic enterprises with production approval, and 18 enterprises are in the production reporting stage. It should be noted that Engelje tablets have been included in the fourth batch of national adoption in February, 2021, which shows the expectations of enterprises for Engelje tablets. However, judging from the global sales of Engelje (US$ 8.2 billion in 2022), the domestic market is far from saturated (over 400 million yuan in 2021).

Under the condition that the single drug track is crowded, some enterprises began to lay out compound preparations. Since this year, seven enterprises have submitted the application for the listing of metformin engeglinide tablets/sustained-release tablets, plus two in 2021, at present, a total of nine enterprises are in the production reporting stage of metformin engeglinide.

It is worth mentioning that although the sales of metformin monotherapy have declined in recent years, it can still be seen everywhere in the market, especially in pharmacies.

At present, the best-selling hypoglycemic compound preparations in the market are mainly metformin plus another kind of hypoglycemic drugs, such as "metformin+sulfonamide urea derivatives", "metformin +DPP-4 inhibitor" and "metformin +SGLT2 inhibitor". In addition, there are more and more combinations of compound hypoglycemic preparations, such as "SGLT2 inhibitor +DPP-4 inhibitor", which has been reported for production by enterprises.

END Author | Ryan Source | Medicine Chunqiu

Experts discuss ＂Fireworks Family＂ Xu Fan Liang Jing Sun Qian interprets the core of the role.


1905 movie network news A seminar on TV series "Fireworks Family" was held in Beijing a few days ago. The competent departments, experts and scholars, broadcasting platforms, representatives of the main creators, starring actors, actors and actresses attended the event. The guests at the meeting discussed the spiritual theme of family growth, the cultural communication value of caring for family reality, and the creative concept, development and changes of family dramas with realistic themes.　


"Fireworks Family" takes the getting along, running-in and common growth of three generations of Meng family as the narrative basis, focuses on different intergenerational parent-child communication modes and typical Chinese mother-daughter relationship, and shows the influence of different family appearances on individuals.


Yang Xiaopei, founder and CEO of Xixi Film, artistic director and chief producer of Fireworks House, said when interpreting the creation process of the drama series: "We all experience these trivial things, but how can we still have hope in these trivial lives? This is a core strength and value that I want to express most in the creation of Fireworks House."


After the broadcast of "Fireworks Family", the distinctive characters of the main characters and the plot of dramatic conflict have caused extensive discussions on the Internet. Xu Fan, the actor of Meng Mingwei in the play, shared that the cooperation between the actors in the whole shooting process was very tacit, just like a harmonious big family giving to each other. "There was a scene where my daughter and mother advised Mingwei to divorce. When I looked into my eyes, I felt absorbed and felt the mutual strength between the actors."


Liang Jing, who plays Meng Yuqing, feels the influence of this woman. In her view, the characters have both a sense of fragility and an absolutely powerful inner world, and at the same time, she knows how to get along with her family. Qian Sun, the actor of Tao Shu-na, also expressed her feelings: "Nana infected the audience with her optimism and courage. Many people said that she was me. I used to feel this way when shooting, but later I found that I was more positive and sunny at that time. This is the energy that Nana gave me."


The guests and scholars at the meeting also put forward their research and thinking on Fireworks House. Hujie, Secretary-General of Youth Working Committee of China TV Drama Production Industry Association, said: "From the narrative type, Fireworks Family has opened up a new paradigm of realistic family drama". In his view, while presenting the family relationship in a panoramic way, the play tells the plight of each individual in the family in a delicate and unique way, which is true, grounded and has the texture of real life flow.


Lv Fan, director of the Audio & Video Office of Peking University Media Center and deputy director of Peking University TV Research Center, thinks that Fireworks Family has achieved three things in terms of aesthetic characteristics: it has returned to the realistic tradition of China family drama, realistically represented the essence of female group images and innovated the connotation expression of the word "fireworks".


Professor Tsinghua University, vice-chairman of the Chinese Literary Critics Association, thinks that "Fireworks Family" is a drama that has been widely concerned by the society and brought about a wide range of social topics. It is a new expansion of family ethics drama. The three generations of female images have their own characteristics, and it is also a breakthrough in the new image of new women. Through a new understanding of the new society, the basic theme of upward goodness has been conveyed. "


Liu Qiong, deputy director of the Literature and Art Department of People’s Daily, said in his speech: "This drama has a particularly distinctive female perspective and female thinking, and it interprets and presents the life state with women as the protagonist. It is of exemplary value in large theme types."


Relive the classics! On July 22nd, the movie channel broadcasted two films ＂Home alone＂ continuously.


Special feature of 1905 film network Whenever he feels frightened, he opens his eyes wide, squeezes his cheeks with his hands, opens his mouth wide and shouts "Ah!"



This classic action of the child star has undoubtedly become a classic scene of this film.After the film was released that year, this action was imitated by children who have seen this film all over the world.


On July 22nd, the movie channel will broadcast for you continuously, which is the American family comedy movie series starring macaulay culkin.


01


As the representative of Hollywood comedies in the 1990s, the series of movies "Home alone" is undoubtedly a classic of the times.This series of movies, known as the classic of family comedy movies, successfully combines family affection and suspense and horror elements to create a richwarmA story of feeling and tension.



As a small-budget children’s comedy film, in 1990, the first "Home alone" cost only $18 million and became the biggest box office dark horse at that time.


The film has been the top box office champion in the United States for 12 weeks in a row, creating a box office record as high as $285 million, which set a new record for the highest box office of Guinness films at that time.



The success of Home alone also made macaulay culkin, who was only ten years old, explode overnight.At an early age, he was nominated for the Golden Globe Award for Best Actor, MTV Film Award, Young Artist Award, etc. He earned as much as $8 million and became one of the hottest child stars in Hollywood.


The story of Home alone is not complicated.Because of negligence, 8-year-old Kevin (macaulay culkin) was left at home by his family who flew to Paris to celebrate Christmas.Without the control of his family, Kevin was very surprised. He ate snacks and watched TV, and made his home an "amusement park".



But soon, loneliness triumphed over excitement. What’s more frightening is that he accidentally discovered that his home has become the target of two stupid thieves.



In order to defend his home, Xiong Haizi waged a funny and thrilling "battle" against the stupid thief, and the drama full of jokes was undoubtedly the climax of the whole film.The two stupid thieves discussed how to teach a lesson at the door without scruple.smallvictoriousWen, as a result, was taught a lesson by his marble gun sticking out of the doorway.



In order to meet the stupid thief, Kevin arranged the trap early:The water spilled on the steps in advance was frozen into bare ice, and as a result, the stupid thief fell black and blue and fell to the sky.



Sticky paint fills the stairs, making it difficult for thieves to walk;



As soon as the stupid thief caught the doorknob, he was burned red. It turned out that Kevin had hung the red-hot soldering iron on the handle inside the door.



When the robber thought he could finally break into the house, he turned on the switch of the flamethrower at the moment of opening the door, and a fire burned him bald.



It is said that countless children wanted to change their names to "Kevin" after watching movies.His wit, courage and cuteness are deeply loved by the audience, and his counterattack and way of dealing with intruders make the children watching the movie cheer.


02


Home alone is not only a simple entertainment film, but also conveys the theme of courage and growth.


The producer of the film once said, "Children really like this film because Kevin in it is just like themselves. Kevin has no superhuman ability, unlike those characters with superhuman powers in other films, which makes children unattainable. "



Kevin’s growing process from immaturity to maturity encouraged the young audience to explore and face the world bravely.During the period of solitude, thisancientquickA strange but calm little adult has learned to take care of himself at home.



The experience of independent life gradually made him confident and brave. Facing the invading enemy, he was willing to defeat his fears and finally successfully defended his home.



Macaulay culkin created a brave, resourceful, intelligent and mature image of children in the new era, which became the object of admiration and envy of children at that time.


"Home alone" not only has a positive impact on children, but also adults can feel the importance of family from the film.



Always remind us to cherish our family, care for our loved ones, and put the happiness of our family in the most important position in our hearts.


Today, at 13:15 and 15:15, the movie channel will continuously broadcast "Home alone" and "Home alone 2" starring macaulay culkin.Xiong Haizi vs. Stupid Thief’s hilarious drama will definitely make you feel the charm of American humor while laughing!


At the same time, during the summer vacation, the movie channel also prepared more movies that are widely loved by teenagers, waiting for you to watch!


Has competitive negotiation been ＂ignored＂

　　　 ■ Qin Zhilong
　　As one of the ways of government procurement, competitive negotiation has many advantages, but it is not widely used in practice. Why? The author tries to analyze this.
　　In 2011, 80.7% of China’s government procurement projects were purchased by public bidding, much higher than other countries. For example, in 2011, the amount of public bidding projects in Germany accounted for about 43.7%, while that in Britain was only 19% and that in the United States was 8%. In 2020, the scale of government procurement in China will be 3,697.06 billion yuan. From the perspective of procurement methods, the scale of public bidding, invited bidding, competitive negotiation, competitive consultation, inquiry and single-source procurement will account for 79.3%, 1.1%, 3.2%, 7.7%, 1.1% and 4.3% of the national government procurement scale respectively.
　　As can be seen from the above data, the amount of public bidding projects in China accounts for about 80%, while the amount of competitive negotiation projects accounts for only 3.2%. In contrast, there is a big gap between the two. The author believes that this is related to the different interests of the parties involved in government procurement.
　　The main reasons why purchasers seldom choose competitive negotiation methods are as follows: First, the publicity of government procurement system is not enough. As a result, buyers are unfamiliar with and do not understand the government procurement system. When it comes to government procurement, they think that public bidding should be held. I don’t know that there are many other procurement methods to choose from. What buyers don’t understand even more is that various procurement methods are just to adapt to different procurement contents, procurement projects and procurement scales. Second, the principle of fairness stipulated in the government procurement law is misunderstood, and it is considered that only public bidding is fair and other procurement methods are unfair. Sometimes, the regulatory authorities also hold this view. Some representatives of purchasers complained and told auditors that when auditing procurement projects, they often asked why public bidding was not used for procurement. Third, it misreads the stipulation in Article 26 of the Government Procurement Law that "public bidding should be the main procurement method of government procurement". It is believed that since the law clearly stipulates that it should be implemented, and public bidding is not limited by applicable circumstances, other procurement methods are limited by applicable circumstances. Therefore, public bidding has naturally become the first choice for purchasers. Of course, it is also one of the reasons that the bidding law was promulgated earlier than the government procurement law.
　　From the agency’s point of view, there are reasons why the internal control system of the agency is not perfect, and it is difficult for the agency to manage the procurement managers, fearing that the irregular operation of the managers will lead to criticism from the regulatory authorities or cause unnecessary doubts and complaints; There are reasons for the lack of professional ability of the managers themselves, because each manager has a lot of items to purchase, so it is difficult to be professional, especially the frequent rotation of managers makes it difficult to improve the professional level, which makes it difficult to accurately grasp the procedures and progress in the negotiation process and lose the advantage of competitive negotiation and procurement; There are also reasons for the negotiation experience of the handling personnel and insufficient understanding of the market situation, and they lack confidence in grasping the negotiation process and giving full play to the advantages of competitive negotiation.
　　Evaluation experts are reluctant to participate in the evaluation of competitive negotiation projects, because the negotiation time is long, and they are particularly worried that one round of negotiations will not be completed and many rounds of negotiations will take a lot of time. The evaluation of public bidding projects is relatively simple, and there is no need to face the suppliers. Even if you are not familiar with the majors involved in the procurement projects, you can score according to the routine requirements and complete the bid evaluation. In other words, it is easier for evaluation experts to fill in the blanks in public bidding projects. Of course, the professional ability of experts is also one of the constraints. Although the expert database has divided the specialties of experts, the technology of the project is becoming more and more complex, and the technical complexity is the main application situation of competitive negotiation procurement. It is difficult for randomly selected experts to meet the professional characteristics of the project, because the expert database is divided according to the major categories, and it is impossible to divide it too finely.
　　For suppliers, competitive negotiation projects are also difficult to deal with. Competitive negotiation is generally conducted on site, but many public bidding projects are basically electronic at present, and almost no links require suppliers to go to the site unless some projects require suppliers to respond on site. In addition, competitive negotiation projects are difficult to control in time, and professionals who know the project best need to come to the site to participate in the negotiations. Unlike public bidding, suppliers can make overall arrangements for the personnel who make bidding documents. In other words, for competitive negotiation projects, suppliers cannot fish in troubled waters. Under normal circumstances, it is easy for the negotiating team to judge whether a supplier really understands the project, especially the technical key points and difficulties of the project. In practice, it is also common for the negotiating team to meet supplier representatives who have "three questions and three unknowns". In fact, it is easier to judge the professional ability and comprehensive strength of suppliers through negotiation, find the suppliers who are really suitable for completing the project, and reduce the procurement risk. A well-written bidding document does not truly represent the ability and level of suppliers, and only written materials sometimes lead to misjudgment.
　　The author believes that competitive negotiation has at least the following advantages: it can shorten the procurement cycle, improve procurement efficiency and make procurement projects play a role faster; Can improve work efficiency and reduce procurement costs; Can conduct more flexible negotiations and reduce procurement risks; It can be handled flexibly according to the actual situation, which is more convenient for the realization of procurement objectives; It can reduce the risk of being manipulated and is more conducive to achieving the value goal of "value for money".
　　The biggest disadvantage of competitive negotiation is that the requirements for procurement personnel are relatively high, and they need to know more about the project information and market conditions, and they need to master certain negotiation skills and experience.
　　The author writes this article in the hope of increasing the application of competitive negotiation procurement through the efforts of all parties involved in government procurement. In addition to competitive negotiation, there are competitive negotiation, inquiry, single source and other procurement methods, but competitive negotiation is a non-bidding procurement method with many advantages, which is worth applying if the situation is suitable.
　　As early as the 2013 National Government Procurement Work Conference, relevant leaders pointed out: "On the one hand, we emphasize public bidding, and the legal time for public bidding takes more than 40 days at the earliest, and the problem of low procurement efficiency has been criticized by the society; On the other hand, many procurement results have not achieved the goal of’ value for money’, and many open tenders have been manipulated. This effect of sacrificing efficiency and not really achieving standardization is seriously incompatible with the efficiency requirements of government administrative system reform. " It is in line with the direction of deepening the reform of government procurement system in China to rationally apply various procurement methods and change the old concept that public bidding is the king.
　　(Author: Shanghai Municipal Government Procurement Center)

Honda Accord’s new changes： power upgrade, design innovation, new car for young people.

In today’s increasingly fierce competition in the automobile market, Honda’s latest change relies onExcellent power system and fashionable design.It has once again aroused widespread concern. The modification of this B-class car not only innovates the power selection, but also pays more attention to the needs of young consumers, making it stand out in the market.

Power system selection

As a medium-sized car, the Accord’s power system is undoubtedly a part of its success. Whether for consumers who love driving or family users who pursue economy and practicality, the choice of power system is very important.

Fuel edition

In terms of fuel power, the new Accord will be equipped with a 1.5T engine and a CVT continuously variable transmission. This combination can not only effectively improve fuel economy, but also ensure the balance of power performance.The main parameters of this power system are excellent: the maximum horsepower reaches 192 horsepower, the peak torque is 260 Nm, and the comprehensive fuel consumption is about 6.6 liters/100 kilometers.. This kind of power output is especially suitable for daily city driving, and it can easily cope with the busy traffic environment without worrying too much about fuel consumption. Whether it’s a daily commute, a weekend trip, or a gathering of friends and relatives, this fuel version of the Accord can well meet the various needs of consumers.

Hybrid version

In addition to the traditional fuel power,Honda will also launch a hybrid version in this redesign.. The new Accord Sharp Hybrid will be equipped with the third generation i-MMD dual-motor hybrid system, showing its perfect balance between power and environmental protection. Its engine has a maximum power of 146 HP and a peak torque of 175 Nm. In addition, the hybrid version has a motor power of 135 kW and a peak torque of 315 Nm. All this comes together, and the combined maximum power reaches 158 kW (215 HP). This means that the hybrid Accord will not only perform well in fuel consumption, but also show amazing strength in acceleration and response. In today’s society that pays attention to environmental protection and economy, hybrid models are undoubtedly more attractive to young consumers.

market positioning

As a representative model of Japanese Sanjie, Honda Accord has a clear market positioning. Whether it is a family car or a business trip, it has always found its own foothold among different consumer groups. However, with the change of market wind direction, the design and function of Accord have gradually catered to the needs of young consumers.

The tenth generation Accord has made a bold breakthrough in design style, from a stable atmosphere to a sporty fashion style. This change in style not only makes people shine, but also shows Honda’s keen insight into the future market.In the upcoming change, it is foreseeable that Accord will continue to use these fashion elements to further cater to the preferences of young consumers.. The body lines are smoother and the front face design is more dynamic, which makes it stand out among many models.

In addition, Honda Accord has always paid attention to the design concept of driving comfort, and this change is no exception. Whether it is the comfort of the seat or the reasonable layout of the interior space, these are aimed at providing better driving experience and ride enjoyment. In many occasions such as family travel and business reception, Accord can bring more convenience and comfort to consumers, which makes people feel at ease.

conclusion

Generally speaking, the new Honda Accord has reshaped its competitiveness in the B-class car market through all-round improvement in power system, appearance design and market positioning.With the rising of young consumers, the new Accord can better meet their aesthetic and use needs, which is expected to lead the brand to the peak again.. In the future market, whether it can continue to maintain its position as a "shoulder handle" remains to be seen.

If you have any views or expectations about the change of Honda Accord, please share your thoughts in the comments section! In this competitive automobile market, the voice of consumers is very important. Let’s participate in this automobile revolution!

Mercedes-Benz GLE coupe in Weifang area is on sale! The reserve price is 792,800, and the discount waits for no one

[Autohome Weifang Discount Promotion Channel] brings you the latest preferential information. At present, in the Weifang market, the high-profile price reduction promotion is being carried out with unprecedented intensity. The maximum discount has reached an amazing 51,000 yuan, which means that the luxury model that originally started with a price of up to 792,800 yuan now has the opportunity to start at a more affordable price. Want to seize this wave of preferential opportunities and explore the best car pickup price? Please don’t miss it, click "Chatty Car Price" in the quotation form now, let’s explore more benefits together!

潍坊地区奔驰GLE轿跑特价出售！底价79.28万，优惠不等人

The Mercedes-Benz GLE coupe sets the trend with an elegant and dynamic design. Its front face is integrated into the classic double kidney-shaped air intake grille of the Mercedes-Benz family, with sharp LED headlights, showing the perfect fusion of power and technology. The body lines are smooth and dynamic, and the coupe-style roof design highlights its unique identity. The overall style is both luxurious and sporty, showing Mercedes-Benz’s new interpretation of luxury SUVs.

潍坊地区奔驰GLE轿跑特价出售！底价79.28万，优惠不等人

The Mercedes-Benz GLE Coupe has a unique body profile with its elegant side lines. The body size is 4941mm*2018mm*1716mm and the wheelbase reaches 2935mm, creating a spacious interior space and a comfortable driving experience. Its tire size is 275/50 R20, and it is equipped with this specification on the front and rear, ensuring excellent grip and driving stability. The clever combination of tires and rims further enhances the overall dynamic and luxurious feeling, making the GLE Coupe even more eye-catching visually.

The interior design of the Mercedes-Benz GLE coupe reflects the perfect fusion of luxury and technology. The exquisite leather steering wheel provides an excellent grip, with manual and electric adjustment functions to ensure driver comfort. The 12.3-inch central control screen has a clear display and is equipped with an advanced automatic speech recognition control system. It supports functions such as multimedia, navigation and telephone, which is convenient for the driver to operate at any time. The seats in the car are made of imitation leather, and the main and auxiliary seats support multi-directional adjustment, including front and rear, backrest, high and low and waist support, providing passengers with a comfortable ride experience. In addition, the front seats are also equipped with heating and ventilation functions, and the driver’s seat is also equipped with a power seat memory function, which further enhances practicality. The rear seats support proportional reclining, providing flexibility for space utilization. Overall, the interior of the Mercedes-Benz GLE coupe features user-friendly design and high-tech configurations to create a luxurious and convenient driving environment for passengers.

潍坊地区奔驰GLE轿跑特价出售！底价79.28万，优惠不等人

The Mercedes-Benz GLE Coupe is equipped with a powerful 2.0T engine with a maximum power of 190 kilowatts and a torque output of 400 Nm. The engine has 258 horsepower and is paired with a 9-speed automatic transmission, providing the driver with a smooth and efficient driving experience.

In this Mercedes-Benz GLE Coupe price promotion, we are fortunate to offer you a very attractive car purchase opportunity. Now is the time to seize this once-in-a-lifetime opportunity to buy this luxury, performance and design car. Mercedes-Benz’s excellent quality and innovative technology, coupled with the affordable price at this moment, will undoubtedly bring you an incomparable price. Don’t let the opportunity pass by, act quickly, drive your Mercedes-Benz GLE coupe, and start a journey of dignity and passion that belongs to you. Mercedes-Benz Home always puts customers at the center and looks forward to your visit to create a better tomorrow.

＂Dragon Horse Spirit＂ exposes clips, Jackie Chan’s Guangzhou roadshow scene ＂remembers bitterness＂


1905 movie network news The movie starring the screenwriter, director,,, and lead is being released, and the film’s box office has exceeded 33 million yuan. Some audiences said bluntly, "Jackie Chan, the most different in the past 60 years, has earned enough tears."


The film recently released a "reluctant to part" feature clip. In the clip, Lao Luo had to part with his beloved horse, Chi Rabbit, because of various obstacles. The picture of "one person and one horse" hugging and saying goodbye was heart-wrenching, and Jackie Chan’s tearful words "You must not forget me" were also particularly poignant.


The movie "Dragon Horse Spirit" revolves around the story of "one person, one horse". Jackie Chan plays the down-and-out Dragon Tiger martial artist Lao Luo, who braves the set with his beloved horse, Red Rabbit, laughing and crying along the way. As Jackie Chan’s most special partner, Red Rabbit not only has absolute action strength, but also has countless fans with its clever and cute personality. In addition, Red Rabbit’s emotional expression also caused the audience to cry, "I didn’t expect that I would cry because of a horse."


In the film, Lao Luo’s "rescue" at the birth of Red Rabbit, to the care and careful cultivation of Red Rabbit from childhood to adulthood, let the audience see the family bond between "one person and one horse" to protect each other. And Lao Luo’s hard work to protect Red Rabbit, and the bridge where he had to say goodbye to Red Rabbit in the end, made the audience cry. Some viewers said, "Every interaction between Lao Luo and Red Rabbit is so touching. Who can hold back crying when they see Red Rabbit chasing the car? Remember to bring more tissues."


In addition, the film’s creator, director Yang Zi, actor Jackie Chan, Liu Haocun, also appeared at the Guangzhou roadshow recently and had a post-screening exchange with the audience. Many Hong Kong film fans came to the scene that day, and they all expressed that they were moved by the part of the movie that paid tribute to Jackie Chan’s classic movie. "I was moved by the spirit of the dragon and tiger martial artist. I was really moved by the previous beat-the-scene. I like Hong Kong action movies very much, so I am very grateful to you for passing on this spirit." Director Yang Zi also shared his feelings with everyone. "I am very nervous and excited to finally be able to bring this film to everyone. If everyone likes this movie, all the hard work will be worth it."


The release day coincided with Jackie Chan’s birthday. Not only did iron fans organize fans all over the world to record "True Hero" and give it to him, but also the audience specially customized a huge cake with a dragon pattern, and there were also students who sent 1,000 blessings. The enthusiastic blessings from the audience made Jackie Chan very moved. "Today is the most happy birthday I have ever heard".

Surprisingly, the brothers of the Chengjia class "ambushed" in the audience that day, giving the eldest brother a happy "surprise". Yuan Biao, a junior brother who was also a member of Qixiaofu, sincerely thanked the senior brother on the spot, so that the eldest brother could not help but "remember the hardships" and shared with everyone the days when everyone suffered together when they debuted.


Jackie Chan entered the industry at the age of 8 and has starred in hundreds of works so far. He is a well-known national idol. At the roadshow, many audience members came to watch with their parents. One audience member said excitedly, "My father likes Jackie Chan very much. Influenced by my father, I grew up watching Jackie Chan movies since I was a child." Brother Jackie Chan warmly concluded that "when I was a child, my father took you to watch plays, and now you take your father to watch plays."

In addition to this, there are also fans who came with their mother to the cinema with tears. "My mother and I have watched your movies for two generations of youth, and I can vividly remember your past movie scenes when watching movies. You are already 69 years old and still insist on making movies, which makes me feel very admired."


Being able to win the love of so many fans is inseparable from Jackie Chan’s brave "jumping down" on the set again and again. The lines in the movie "It’s easy to jump down, but difficult to walk down" have pierced the hearts of many fans.

At the scene, the eldest brother also shared his understanding of this line. "I used to feel that I could do it, but one day I wanted to do it and suddenly found that I couldn’t, and at that moment I suddenly felt that I was old. At the same time as accepting this fact, I thought I would change everyone’s opinion of me. So I started filming, a person who is greedy for life and fear of death, to an old master, and now an old dragon and tiger martial artist, I have been changing. So I am very happy to be able to film this drama and show it to everyone with my performances and actions."


On that day, many brothers in the family class secretly came to the roadshow to create a birthday surprise for the eldest brother, and also sent a pennant "Big Brother Forever", saying that "only if there is a big brother can we become a family class". When the eldest brother saw the brothers, he couldn’t hide his joy and introduced his brothers to the audience one by one, and the atmosphere was very warm.

Yuan Biao, who debuted at Qixiaofu together with his eldest brother, sincerely thanked his eldest brother, "I was brought to debut by my senior brother, and later he became a martial arts instructor. I said I will fight hard with you, he said yes, I will follow him, without me as the boss, you will not know me."


Seeing the brothers who shared weal and woe, the eldest brother couldn’t help but "reminisce", "Yuan Biao and I hit the railing on the second floor and fell down. There were no protection measures, all of them were real glass. No one cared about us, only he helped me up, and after taking a shower at night, my body was full of pain, and the glass was forked in." Many Hong Kong film fans expressed "heartache".

In addition to the friends who came to the scene, there were also many friends who could not attend who sent birthday wishes in the form of a video. The eldest brother was moved and said, "I am really happy, and I am surprised every time. I often wonder how I can let so many people pay for me. Thank you for supporting me for so many years."


The M5 series is a high-performance SUV in the new energy field with no short board in all directions.

　　　Modern automobile consumers often feel entangled when choosing vehicles, and the fuel consumption of fuel vehicles is high, which is unbearable for wallets; But they are worried about the endurance and performance of new energy sources. Even if I make up my mind to choose a new energy vehicle, I feel confused when I choose which one. After all, as an important travel partner, the endurance, performance and dynamic performance of the vehicle are directly related to the experience of the whole trip. In fact, if you want to solve this problem, you only need to choose a model with excellent comprehensive strength, and the M5 series of Wenjie is a high-quality choice worthy of consideration.

　　Endurance, travel without worry

　　Whether it’s poetry and distance or daily commuting, the M5 series can meet your needs. Thanks to the intelligent extended-range technology, the comprehensive cruising range of the standard version of the M5 series rear-drive vehicle can reach 1455km when it is fully charged. Normally, a tank of fuel for a domestic fuel vehicle can support a journey of 500-600 km at most, but the data of the M5 standard version of the vehicle can be said to be super doubled. With a cruising range of 1455km, you can go to go on road trip as soon as you want. Whether you start from Beijing and drive all the way west to Xi ‘an to experience the Tang Dynasty, or start from Shanghai and go south to Guangzhou to experience Cantonese morning tea, the M5 series in Wenjie can accompany you across the mountains and seas, and you don’t need to replenish energy to have fun all the time.

　　If you don’t like to travel far, you like to feel lucky in your own world. The M5 Smart Driving Edition can help you explore your city with the lowest cost. The pure battery life of the M5 Smart Driving Edition reaches 255km. Even in Beijing, it is more than enough to commute for one week by going back and forth for 30km every day. More importantly, the charging efficiency is high, and it can be charged from 20% to 80% in half an hour. Occasionally, it is absolutely appropriate to go camping for a short distance on weekends and live on pure electricity.

　　Full power, popular electric switch

　　Compared with traditional fuel vehicles, Wujie M5 series can not only reduce the travel cost for users, but also provide double endurance, and its performance is unambiguous. Take the M5 standard four-wheel drive model as an example. The acceleration time of this car is only 4.4 seconds, which is better than many luxury brand electric SUVs on the market. The biggest benefit of such excellent data performance is super explosive power, which allows drivers to experience the passion of driving a sports car.

　　Super explosive power is also related to the dynamic performance of the vehicle itself. The maximum power and peak torque of the M5 standard four-wheel drive model can reach 365kW and 675N·m respectively. In daily life, when the pressure is great, drive this car to release it, feel the speed and passion, relieve the pressure, forget the troubles and regain the passion.

　　The strong performance of the M5 series in the world benefits from the blessing of the three-in-one electric drive system of HUAWEI DriveONE. This system adopts the industry’s first precision oil cooling technology, which has a better cooling effect on key components under the same power and torque. The direct benefit is that it can fundamentally improve the power and quietness of the car. If you drive fast at high speed, or speed up overtaking, the power is on call.

　　In addition, Wujie M5 version also has HUAWEI DATS dynamic adaptive torque system, which can reduce the pre-driving impulse by 31%, the sloshing convergence time by 46% and the system response time delay to 4 ms.. When driving on potholes or bumpy roads with speed bumps, not only can the car body shake slightly, but it can also stabilize quickly. If the self-driving trip encounters bumpy roads such as mountain roads and gravel roads, it can also pass comfortably, alleviating the discomfort caused by bumps in the car. If you are driving on a road with many curves, this system can help the vehicle to improve the lateral force through adaptive torque adjustment, and the risk of tail flick will be greatly reduced when driving, which is stable and safe.

　　The M5 series has brought excellent performance to users in all directions. It can make you say goodbye to all kinds of troubles and enjoy a worry-free driving journey in terms of endurance, power and driving control. If you are eager to travel without worry and enjoy driving, you may wish to try the M5 series. I believe it will bring you a different surprise experience. In addition to the surprise experience brought by the product itself to users, the recent delivery speed is also very surprising. You can pick up the car within two weeks after making a decision. You may wish to experience it in the offline test drive!

Reading ｜ Young People’s ＂Partner＂ Socialization

　　* This article is the 11th issue of Pindu in 2023.

　　I ran into an acquaintance, but I didn’t see him for more than a month and thought he had lost a lot of weight, so I asked him for advice on the secret of losing weight. He told me: "I found some partners to lose weight, ran together and ate fat-reducing meals. Everyone encouraged and supervised each other every day. I didn’t expect the effect to be quite obvious."

　　Weight loss partner? Seeing my doubts, my acquaintances told me with a smile that compared with my friends, the utility of "partner" is more clear, and it can be accurately subdivided, such as "meal partner", "game partner" and "gym partner". That is, from the joint participation of something, it ends at the end of cooperation; Highly in tune with a certain field, but emotionally independent. Because we only concentrate on the matter itself, we are both relaxed. The acquaintance said happily: "This time, I lost weight successfully, and’ Zuozi’ contributed a lot. The purpose of getting together is to lose weight. If you lose weight successfully, the mission of’ taking the child’ will be completed, and it will be automatically dissolved. There is no trouble with the relationship. "

　　I am a person who seems to have a "flattering personality". Every time I go out with my friends, I always habitually compromise. For example, if I want to stay in a hotel and my friend wants to experience a B&B, then go to the B&B, even though it makes me feel unsafe, I may not sleep well all night. I wanted to taste local specialties, but my friend couldn’t get used to it and asked for a change of fast food, so I stopped insisting and just ate at will. I plan ahead and want to visit more scenic spots, but my friend is tired and prefers to sleep in his room, so stay in his room and play with his mobile phone in another place.

　　With the "partner", it is completely different. You are used to staying in a hotel, and I am used to staying in a hotel; You like to eat special food, and I like to try it. You are energetic and want to look around, and I also want to visit all the scenic spots … We are in tune with each other in terms of tourism. If it’s not in tune, then find another one who is in tune, and no one has to accommodate anyone. The original purpose of everyone is to find people with the same hobbies and have a good time. If you are happy, I will be happy.

Reading | Young People's "Partner" Socialization

　　I have read Xu Zhimo’s poem: You and I meet in the dark sea/You have yours/I have mine/direction/You remember it/You’d better forget it/The light that shines on each other at this meeting … This poem is very suitable for describing the relationship between partners. After meeting each other, the vast majority of the results are forgotten, but some will remember, and thus further develop.

　　Xiaoyuan is an example. When she announced her engagement in a circle of friends, many of her friends were surprised. Everyone knows that Xiaoyuan has always been in fear of marriage, and has declined many people’s kindness to introduce her boyfriend. Why did you suddenly change your mind? Xiaoyuan told everyone shyly that some time ago, she found a "book partner" to read together and exchange reading feelings. This "book partner", like Xiaoyuan, especially likes reading, and they have similar views and have the same view on many things. Because there is no burden of "making friends", Xiaoyuan gets along with each other easily and happily, and unexpectedly discovers the "interesting soul" of each other. It happened that the other party also felt this way, so they naturally developed from "partners" to male and female friends until they "made a positive result."

　　In fact, "partner" socialization is a kind of "shallow socialization" above strangers and below friends. This kind of relationship can not only inspire each other, but also cause no extra burden to each other because of the sense of boundary, which is very suitable for busy young people with increasing pressure. If you want to get rid of a person’s loneliness quickly, it is still feasible to find a precise companion.

　　Author: Qiao Kaikai

[Editor in charge:

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World refitted car industry grand meeting： Counting ten cool car models of North American refitted car show.

　　　　　

　　　 [Content at a glance]At this modified auto show, Volvo exhibited two high-performance modified Volvo S80 and C30, operated by Heico Sportiv, a famous German modified car manufacturer.
Heico’s modified C30 uses an upgraded T5 turbocharged engine.





　　　　The 2007 North American Modified Auto Show (SEMA) was held in Las Vegas, USA from October 30th to November 2nd. After 31 years’ development, this annual modified auto show has become a grand event of the world’s modified car industry, attracting most of the world’s automobile manufacturers and hundreds of thousands of car enthusiasts to gather in Las Vegas every November.


　　　　So far, there are no manufacturers in China, but with the growth and prosperity of China’s automobile aftermarket, the world’s largest modified auto show is gradually entering the field of vision of China players. It doesn’t matter if you can’t come to the scene in person. Now, follow our reporter and take a look at the world’s most advanced automobile modification technology and products.


　　　　Chevrolet Cobalt SS


　　　　The 2008 Cobalt SS is equipped with the same 2.0-liter Opel and Ecotec 260hp turbine engines as Chevrolet HHR SS, Opel Astra OPC and Pontiac Solstice. The output power is 55 horsepower higher than that of the previous super-powered Cobalt SS, and the acceleration process from 0 to 100 km/h takes only 5.7 seconds.


　　　　Volvo S80 and C30


　　　　At this modified auto show, Volvo exhibited two high-performance modified Volvo S80 and C30, operated by Heico Sportiv, a famous German modified car manufacturer.


　　　　The modified S80 high-performance concept car adopts T6 turbocharged bioethanol engine, which outputs 350 horsepower at 5500 rpm, with the maximum torque of 550Nm/1500~4000rpm and the acceleration time of 0~100 km/h of about 5.8 seconds.


　　　　It is equipped with Volvo electric control all-wheel drive system with instant traction function, and also adopts specially developed sports suspension.


　　　　Heico’s modified C30 uses an upgraded T5 turbocharged engine. The maximum output power is 300 HP at 5500 rpm, and the maximum output torque is 420 Nm at 3500 rpm. The acceleration time from 0 to 100 km/h is only 5.4 seconds, and the maximum speed reaches 250 km/h (speed limit). The car also uses a specially developed sports suspension.


　　　　Hyundai Elantra "Beach Cruiser" Concept Car


　　　　The hatchback Elantra will be launched in 2008. At this SEMA Auto Show, it made its debut as the concept car of Elantra Touring "Beach Cruiser". This beach cruiser was modified by K-Daddyz Kustomz.


　　　　The car body is painted in two colors, beautiful grape purple and tango orange, with beautiful patterns. The concept car is equipped with a huge panoramic skylight on the roof, and the interior is also made of two-tone high-grade leather. A specially installed 8-channel stereo is installed in the trunk, and high-end speaker components are hidden under the floor of plexiglass. There is no special investment in performance modification, except for the cold air intake system, balance bar and beautiful hood, as well as some small accessories.


　　　　Suzuki SXForce concept car


　　　　This is a brand-new concept car based on the SX4 sports car in 2008.


　　　　Compared with the prototype, SXForce adopts a 5-speed manual transmission, a 2.0 turbocharged engine, the power is increased to 255 horsepower, and an adjustable NASCAR-style tail is added at the tail.


　　　　You can even find a built-in data statistics system, which can help you analyze and download all the information of the engine in real time, and make you feel like you are in the competition.


　　　　Cadillac CTS sports concept car


　　　　At this auto show, Cadillac gave this CTS sports car a brand-new appearance through a series of modifications, including: adopting brand-new front and rear bumpers, improved hood, rear tail and 20-inch rims.


　　　　Carbon fiber parts used in many parts of the car body, redesigned headlights, high-performance brakes with yellow calipers, LED brake lights and exhaust system were replaced with Corsa cat-back exhaust system with 3.5-inch exhaust pipe.


　　　　Ford Roush P-51A mustang


　　　　This car is equipped with Roush Stage3 suspension, powered by an improved ROUSH 4.6L V8 engine, with a maximum power of at least 510hp and a maximum torque of at least 691Nm, so the P-51A should be very competitive. Of course, the full set of Roush aerodynamic kit, upgraded wheels and tires, and upgraded braking system are all included in this upgrade package.


　　　　Hummer H2 Safari


　　　　This is a strong Hummer and a super convertible. The car has no back seat, and the purpose of modification is to use it for competition.


　　　　This Hummer off-road concept car is equipped with a 6.2L V8 engine with 393 horsepower. In addition, the designer has improved the shape of the car, including customized air induction system, customized double exhaust pipe system, wheel flash, protective steel, high-performance brake pads and 20-inch wheels.


　　　　Jeep brings two concept cars.


　　　　At this year’s SEMA Auto Show, Jeep exhibited two Jeep concept cars: Jeep Wrangler Ultimate and Jeep Wrangler JT.


　　　　Wrangler Ultimate is based on Wrangler’s four-door non-limited edition model, equipped with 3-inch body lifting kit and 35-inch BF Goodrich mud tires, 18-inch aluminum alloy wheels, as well as a series of appearance upgrade kits, adding new entertainment systems. The engine adopts a powerful 392 Hemi engine.


　　　　Jeep, on the other hand, is a JT made by removing the rear seat and installing a 5-foot-long cargo box on the basis of the four-door Wrangler non-limited edition. It is equipped with front and rear bumpers and spare tire placement equipment from Mopar, Warn 9500ti winch. (Zhou Weili)

Editor: Tian Shijia